If you are no longer using Lightroom 3 then it is safe to go ahead and get rid of it. If you are on a PC you will probably want to use the Windows uninstall feature to remove it. I cannot speak for the procedure on the Mac since I have never used one. Lightroom 4 is a completely separate program that does not depend upon the previous version. It's probably a good idea for you to keep a record of the serial number for Lightroom 3 in case you need to reinstall at some future date. If your Lightroom 4 was truly an upgrade version then a reinstall could require the original Lightroom 3 serial number as well as the one for Lightroom 4.
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